John Cassel, was born in Johannesburg, South Africa in 1921. He received an MD from the University of Witwatersrand. He joined the new Institute of Family and Community Health at the University of Natal, in Durban. His early work on the health of a Zulu population taught him the importance of cultural forces in the determination of disease etiology and health care delivery. 1953 he left South Africa to obtain further training in public health at UNC. His belief in the importance of the social environment as a determinant of the distribution of health in populations was greatly influenced in his experience in the practice of medicine in South Africa, proved both innovative and controversial in the United States at that time.