After receiving a PhD in Computer Science, Matthew Suderman began postdoctoral research in bioinformatics and epigenetics at McGill University. There he analyzed genome-wide DNA methylation and transcriptional profiles from a variety of tissues and organisms for associations with various exposures and disease states. These analyses suggested that blood DNA methylation profiles may be used to piece together exposure histories to better predict later health outcomes, but that further progress would require analysis of methylation profiles from large, well-characterized human cohorts. This led to his appointment as a researcher and later lecturer at the University Bristol to analyze epigenetic profiles derived from human cohorts under the supervision of Caroline Relton. He has completed software tools to complete these analyses, including meffil (https://github.com/perishky/meffil).