Occupational
Occupational Exposure to Ultraviolet radiation and Cataract Risk in Denmark Chisom N. Iwundu* Chisom Iwundu Johnni Hansen Anne L. Coleman Julia E. Heck
Introduction: Ultraviolet (UV) radiation has been implicated as a contributing factor to lens opacities, with occupational exposure to UV radiation raising concerns for individuals across various industries. Despite this, the relationship between workplace UV radiation exposure and the risk of cataract development remains understudied. Our goal is to investigate the association between occupational UV radiation exposure and the risk of cataract development, using a large-scale population-based study.
Methods: In this cohort study, validated datasets nationally representative of the Danish population were linked based on a unique ID, applied to all residents. Employment history was identified through the Supplementary Pension Fund register, which keeps historical records on each job held, including dates and type of industry for all employees since 1964. UV radiation was assessed using a Danish job-exposure matrix which was applied to the individual employment history. Demographic information, covariates, such as sex, birth year, and region of birth were derived from the Central Population Registry. Cataract diagnosis was retrieved from the National Patient Register (International Classification of Diseases (ICD-8 & 10). Cox regression models were used to estimate the risk of cataract among workers exposed to UV radiation.
Results: Using the linked databases (N=4,142,173 employees), cataract diagnosis was reported in 2.7% of the population. Preliminary results suggest increased risk of cataract among workers exposed to UV radiation (Hazard Ratio: 1.53; 95% Confidence Interval: 1.47-1.56), after adjustment for diabetes and birth year.
Conclusion: Cataract, a leading cause of visual impairment worldwide, poses a significant public health concern in UV-exposed workers. The findings raise additional concerns for worker protection in such jobs.