Sean Hennessy, PharmD, PhD is a Professor of Epidemiology and of Systems Pharmacology & Translational Therapeutics, Director of the Center for Pharmacoepidemiology Research and Training, Director of the Pharmacoepidemiology Concentration of the Master of Science in Clinical Epidemiology Program and a Senior Scholar in the Center for Clinical Epidemiology & Biostatistics at the University of Pennsylvania Perelman School of Medicine. His research focuses on the health effects of drug-drug interactions and the development and evaluation of research methods. He co-leads the Applied Surveillance Core of the FDA-funded Sentinel Initiative. He has served as president of the International Society for Pharmacoepidemiology, as chair of the Drug Safety Scientific Section of the American Society of Clinical Pharmacology and Therapeutics (ASCPT), and on FDA’s Drug Safety and Risk Management Advisory Committee. He currently serves on ASCPT’s Board of Directors and as Editor for the Americas of the journal Pharmacoepidemiology and Drug Safety. In addition to his research and teaching, he leads a clinical program to improve outpatient medication use within the University of Pennsylvania Health System.