Cardiovascular
The long term trend incidence of Stroke in Benign Prostatic Hyperplasia patients: a population-based descriptive study in Taiwan Wei-Ting Wang* Wei-Ting Wang Fu-Huang Lin Yu-Ching Chou
The long term trend incidence of Stroke in Benign Prostatic Hyperplasia patients: a population-based descriptive study in Taiwan
Wei-Ting Wang1 , Fu-Huang Lin1 , Yu-Ching Chou1*
1School of Public Health, National Defense Medical Center, Taipei, Taiwan
*Corresponding author: trishow@mail.ndmctsgh.edu.tw
Background: Stroke is one of the top ten causes of death in Taiwan, while benign prostatic hyperplasia (BPH) is the most common urological disease among aging men. Studies have shown a potential association between BPH and cardiovascular diseases. However, there is a lack of research targeting the Taiwanese population. This descriptive study utilized the Taiwan National Health Insurance Research Database to investigate the incidence of stroke with BPH in a large, population-based Taiwanese cohort.
Methods: A descriptive study was conducted using data from Taiwan’s National Health Insurance Research Database between 2000 and 2013. A total of 44,533 new cases of BPH were identified . Chi-square tests were used to evaluate the incidence of stroke among BPH patients across different age groups and time periods. For long-term trends, changes in incidence over the 14-year period were assessed using linear trend analysis.
Results:. The incidence of Stroke among BPH patients increased from 2.5 per 1,000 person-years in 2000 to 6.49 per 1,000 person-years in 2013, with an average incidence of 4.96 per 1,000 person-years.. After dividing the cohort into four age groups, the stroke incidence rates per 1,000 person-years were as follows: 1.18 for ages 40-49, 1.95 for ages 50-59, 4.34 for ages 60-69, and 6.52 for ages ≥70. The incidence of stroke increased with age.
Conclusion: Over the past 14 years, the incidence of Stroke with BPH has significantly impacted daily life. Using big data, our findings revealed that the incidence of stroke among BPH patients is steadily rising. Future studies are needed to test our hypothesis and further evaluate the association between BPH and stroke.
Keywords: Benign prostatic hyperplasia (BPH), National Health Insurance Research Database (NHIRD).
