LATEBREAKER
Perinatal & Pediatric
Cerebral Palsy and the Hispanic-Immigrant paradox in California Births From 2000-2015 Giselle Bellia* Giselle Bellia Zeyan Liew Haoran Zhuo Tormod Rogne
Abstract
Introduction: Previous studies have shown significant racial disparities in Cerebral Palsy (CP) outcomes. Although, the Hispanic population is understudied despite it being the fastest growing minority group in the U.S. Data shows poorer general health outcomes among U.S.-born Hispanic women compared to their foreign-born counterparts. This analysis aims to investigate whether incidence of CP in Hispanic women’s offspring differed by the mother’s birthplace.
Methods: This statewide cohort study investigated live births that were registered in the California birth records during 2000 to 2015 and were linked to California Department of Developmental Services (DDS) records. Non-Hispanic mothers were excluded from the primary model, resulting in a cohort of 4,233,966 births containing 5,476 CP cases. A sensitivity analysis of only Mexican mothers included 3,514,470 births and 4,515 CP cases. Multivariable logistic regression models were used to estimate odds ratios for CP diagnosis by maternal nativity, adjusting for sex, birth year, mother’s age and education, father’s age, trimester of prenatal care onset, parity, and multiple births.
Results: CP was 12% more likely to occur in the offspring of U.S.-born Hispanic mothers compared with the offspring of foreign-born Hispanic mothers (OR = 1.12; 95% CI: 1.05-1.19). Similar results were found for Mexican mothers (OR = 1.13; 95% CI: 1.05-1.21) where odds of CP diagnosis were greater among U.S.-born mothers.
Conclusions: In line with previous research into other health outcomes, CP was more likely to be diagnosed in the offspring of Hispanic women born in the U.S. compared to offspring of foreign-born Hispanic women. Future policymakers and investigators working with Hispanic populations should carefully consider how mothers’ nativity might be affected by policy and influence developmental disorder outcomes, including for neurological disorders such as CP.
