COVID-19 Pandemic
Determinant of covid-19 vaccination coverage and post-vaccination adverses effects among at-risk people in DRCongo Remy Mpulumba Badiambile* Remy MPULUMBA BADIAMBILE Jean-claude Musasa kasongo Patrick Mukendi Kalonji Crispin Tshishimba Kamwandjemba Jean-Marcel Manongo Bakenge Guy Sakaji Ikomba Musau Sebastien Njila Tshipamba Criss Koba Mjumbe
Contexte. vaccination against Covid-19 is considered as an effective way to reduce the spread of the SARS-CoV-2 and prevent severe complications among the people at risk. however, for vaccination to be effective, it is crucial to have sufficient vaccination coverage within a population. The objective was to determine the factors influencing the COVID-19 vaccination coverage and the occurrence of post-vaccination adverse symptoms among people at risk in Mbujimayi. Methods. A cross-sectional study was employed. The data were obtained via an electronic questionnaire supplied by smart phone between October 2023 and December 2023, where a total of 560 people at risk from the Bonzola health zone were recruited. Logistic regression analysis was used using SPSS version 25.0 to analyze the factors associated with COVID-19 vaccine uptake and occurrence of post-vaccine symptoms. Result.Overall, 560 people at risk (173 females (30.9%), 387 males (69.1%) with a median age and standard deviation of 30.0 years ± 16.9. The overall vaccine coverage was 77 % and 57.7% had post-vaccine symptoms. profession, sex, age, information, raison taking vaccine were the factors that influenced the COVID-19 vaccine uptake. Profession,vaccine dose ,vaccine type were the factors that influenced the post-vaccine symptoms among people at risk in Mbujimayi. People at risk informed for covid-19 vaccination (odds ratio-OR = 0.89; confidence interval-CI: 0.82, 0.96, p < 0.000) were more likely than People at risk not informed to be fully vaccinated. Conclusion. These results emphasize the importance of continuing to raise awareness among at-risk populations on the importance of vaccination to reduce the effects of the pandemic, while considering individual factors that may influence vaccination coverage and post-vaccine symptoms. Additional efforts to enhance vaccination uptake are needed to improve the COVID-19 vaccination coverage.
Keywords: COVID-19 vaccination; Coverage; post-vaccination; adverse symptoms; DRCongo