This list consists of links to articles which are essential in learning basics of the emerging integrative field of “molecular pathological epidemiology (MPE)”.
Ogino S, Chan AT, Fuchs CS, Giovannucci E. Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field. Gut 2011;60:397-411.
(This is the first comprehensive concept paper in the MPE field, and also explains the GWAS-MPE approach.)
Field AE, Camargo CA Jr, Ogino S. The merits of subtyping obesity: one size does not fit all. JAMA 2013;310:2147-2148.
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(This viewpoint paper explains the MPE approach for non-neoplastic diseases such as obesity as an outcome.)
The unique disease principle, the fundamental theory behind MPE, which goes along with the Precision Medicine Initiative of NIH.
Ogino S, Lochhead P, Chan AT, Nishihara R, Cho E, Wolpin BM, Meyerhardt JA, Meissner A, Schernhammer ES, Fuchs CS, Giovannucci E. Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease. Mod Pathol 2013;26:465-484.
Chatterjee N, Sinha S, Diver WR, Feigelson HS. Analysis of cohort studies with multivariate and partially observed disease classification data. Biometrika 2010;97:683-698.
Rosner B, Glynn RJ, Tamimi RM, Chen WY, Colditz GA, Willett WC, Hankinson SE. Breast cancer risk prediction with heterogeneous risk profiles according to breast cancer tumor markers. Am J Epidemiol 2013;178:296-308.
Begg CB, Seshan VE, Zabor EC, Furberg H, Arora A, Shen R, Maranchie JK, Nielsen ME, Rathmell WK, Signoretti S, Tamboli P, Karam JA, Choueiri TK, Hakimi AA, Hsieh JJ. Genomic investigation of etiologic heterogeneity: methodologic challenges. BMC Med Res Methodol 2014;14:138.
Ogino S, King EE, Beck AH, Sherman ME, Milner DA, Giovannucci E. Interdisciplinary education to integrate pathology and epidemiology: Towards molecular and population-level health science. Am J Epidemiol 2012;176:659-667.
AJE-sponsored Symposium at SER Meeting in June 2013
Kuller LH, Bracken MB, Ogino S, Prentice RL, Tracy RP. The role of epidemiology in the era of molecular epidemiology and genomics: Summary of the 2013 AJE-sponsored Society of Epidemiologic Research Symposium. Am J Epidemiol 2013;178:1350-1354.
Symposium at ASPO Annual Meeting in March 2014
Epplein M, Bostick RM, Mu L, Ogino S, Braithwaite D, Kanetsky PA. Challenges and opportunities in international molecular cancer prevention research: A report from the ASPO Molecular Epidemiology and the Environment and International Issues in Cancer Interest Group. Cancer Epidemiol Biomarkers Prev 2014;23:2613-2617.
http://cebp.aacrjournals.org/content/23/11/2613.abstract (full text freely available at Pubmed Central in Nov 2015)
The Second International MPE Meeting in December 2014
Ogino S, Campbell PT, Nishihara R, Phipps AI, Beck AH, Sherman ME, Chan AT, Troester MA, Bass AJ, Fitzgerald KC, Irizarry RA, Kelsey KT, Nan H, Peters U, Poole EM, Qian ZR, Tamimi RM, Tchetgen Tchetgen EJ, Tworoger SS, Zhang X, Giovannucci EL, van den Brandt PA, Rosner BA, Wang M, Chatterjee N, Begg CB. Proceedings of the second international molecular pathological epidemiology (MPE) meeting. Cancer Causes Cont 2015;26:959-972.
http://link.springer.com/article/10.1007%2Fs10552-015-0596-2 (full text freely available at Pubmed Central in July 2016)